ONLINE CURRICULUM VITAE
Jeffrey K. Huang, Ph.D.
Current Position: Provost’s Distinguished Associate Professor, Georgetown University
Address: Regents Hall, Room 406, Georgetown University, 37th and O St., NW, Washington, DC 20057
Website: https://www.huang-lab.com/
Email: [email protected]
Twitter: @jeffreyhuang
EDUCATION
Ph.D. (2003) Mount Sinai School of Medicine
M.S. (1996) Roswell Park Cancer Institute/SUNY at Buffalo
B.S. (1994) Washington University in St. Louis, St. Louis, Missouri
PROFESSIONAL EXPERIENCE
HONORS AND AWARDS
PROFESSIONAL SERVICE
Peer Reviewer
Ad hoc grant reviewer: Regenerative Rehabilitation (RRD0), Dept. of Veterans Affairs.
ZRG1 MDCN-G (03), NIH, NJ Brain Commission on Brain Injury Research, Spinal Cord Injury Research Program (SCIRP), CDMRP, UK Multiple Sclerosis Society, MRC UK, BBSRC UK, International Progressive MS Alliance, ARSEP French MS Society, Telethon Italy
Ad hoc journal reviewer: Nature Chemical Biology; Journal of Neuroscience; Journal of Neurochemistry; Experimental Neurology; Neuropharmacology; Frontiers in Neuroscience; Acta Neuropathologica; Cell and Molecular Neurobiology; Alcoholism: Clinical and Experimental Research; NeuroReport; Annals of Neurology; Neuroscience; Rejuvenation Research; Journal of Neuroscience Research; Journal of Biomedical Sciences; Acta Neuropathologica Communications; Brain Communications; Nature Communications; Neurochemical Research; Journal of Neuroimmunology; Frontiers in Cell and Developmental Biology
Editorial
Symposium Organizer
RESEARCH SUPPORT
Active
Completed
PUBLICATIONS
PATENTS FILED
INVITED TALKS/SEMINARS
UNIVERSITY SERVICE
University
Departmental
GRADUATE COURSES
BIOL-516 – Neuro Journal Club (1 credit), Fall/Spring 2020–Present
BIOL-516 – MCB Journal Club (1 credit), Fall/Spring 2016, 2017, 2018, 2019.
GUEST LECTURES (graduate and undergraduate)
NSCI-558 - Molecular Mechanisms of Neurodegeneration, Spring 2020, 2021, 2022, 2023. Senescence
NSCI-558 - Molecular Mechanisms of Neurodegeneration, Spring 2019. Multiple Sclerosis
NSCI-503 – Systems & Cognitive Neuroscience (3 credits), Spring 2018, 2019. Glia and multiple sclerosis
BIOL-508 – Integrated Biology Core Course (3 credits), Spring 2017, 2018. Neuron-glia interactions
IPN Summer Course, Summer 2015. Glia Biology and Glia-Neuronal Interactions
BIOL-370 – Neurodisorders, Spring 2014. Multiple Sclerosis
IPN NeuroFest, Summer 2013-2016. Oligodendrocyte-neuron interactions
Fundamentals of Neuroscience, GU High School Program, Summer 2013. Glial cells of the nervous system
PHIL-020 – Intro to Philosophy, Spring 2013. Philosophy of science
PH.D. THESIS STUDENTS
Mia Cozart, Biology Graduate Training Program (2020–Present)
Zeeba Manavi, Biology Graduate Training Program (2020–Present)
Phillip Gross, IPN Graduate Training Program (2019–Present)
Joan Reger, Biology Graduate Training Program (2018–Present); Co-advisor: Meng Meng Fu, NIH
George Melchor, IPN Graduate Training Program (2018–Present)
Lauren Rosko, IPN Graduate Training Program (2017–2021).
Jingwen Hu, Biology Graduate Training Program (2016–Present).
Stephanie Davis, IPN Graduate Training Program (2015–2018)
Vivianne Morrison, IPN Graduate Training Program (2014–2019).
Kelly Chamberlain, IPN Graduate Training Program (2013–2016).
CO-ADVISEES
Danna Cunningham, IPN Graduate Training Program (2022–Present). Co-supervisor Dr. Bill Rebeck, Neuroscience, GUMC
Nathanael Lee, IPN/NIH Graduate and MD/PhD Program (2015–2019). Co-supervisor with Dr. Daniel Reich, NINDS/NIH
Jeremiah Paskus, IPN/NIH Graduate Training Program (2015–2019). Co-supervisor Dr. Katherine Roche, NINDS/NIH
POSTDOCTORAL FELLOWS/RESEARCH STAFF
Nataliia Shults, M.D./Ph.D. (2020–Present)
Mi-Hye Lee, Ph.D. (2019–2023)
Erqiu Li, Ph.D. (2019–2021)
Maryna Baydyuk, Ph.D. (2017–Present)
Reiji Yamazaki, Ph.D. (2017–2020)
Rafal Olszewski, Ph.D. (2013–2014)
Konstantina Psachoulia, Ph.D. (2013–2016)
Sonia Nanescu, Ph.D. (2013–2018)
UNDERGRADUATE COURSES
BIOL-414 – Neurodisorders (3 credits), Fall 2016–Present
BIOL-363 – Cell Biology (3 credits), Spring 2015, 2017, 2018, Fall 2022
BIOL-170 – Cell and Developmental Biology (4 credits), Spring 2013, 2014
BIOL-424 – Regenerative Biology and Medicine (3 credits), Fall 2013, 2014, 2015
BIOL-401 – Senior Seminar in Biology (1 credit), Fall, 2013, 2014, 2015
BIOL-341 – RISE-I:Rsrch Intsv Sr Exprnce (3 credits), 2013–Present
BIOL-300 – Research Tutorial (3 credits), 2013–Present
COMMUNITY OUTREACH
PRESS
Address: Regents Hall, Room 406, Georgetown University, 37th and O St., NW, Washington, DC 20057
Website: https://www.huang-lab.com/
Email: [email protected]
Twitter: @jeffreyhuang
EDUCATION
Ph.D. (2003) Mount Sinai School of Medicine
M.S. (1996) Roswell Park Cancer Institute/SUNY at Buffalo
B.S. (1994) Washington University in St. Louis, St. Louis, Missouri
PROFESSIONAL EXPERIENCE
- Deputy Director, Center for Cell Reprogramming, Georgetown University Medical Center, Washington, DC. 2020–
- Associate Professor, Joint Appointment, Dept of Pathology, Georgetown University Medical Center, Washington, DC. 2019–
- Associate Professor, with tenure, Dept of Biology, Georgetown University. 2018–
- Faculty Member, Institute for Soft Matter Synthesis and Metrology, Georgetown University. 2018–
- Faculty Member, Center for Cell Reprogramming, Georgetown University Medical Center. 2018–
- Training Program Faculty, Department of Pharmacology, Georgetown University Medical Center. 2017–
- Training Program Faculty, Center for Neural Injury and Recovery, Georgetown University Medical Center. 2013–
- Training Program Faculty, Interdisciplinary Program in Neuroscience, Georgetown University Medical Center. 2012–
- Assistant Professor, tenure-line, Dept of Biology, Georgetown University. 2012–2018
- Senior Research Associate, University of Cambridge, Cambridge, UK. Advisor: Robin J.M. Franklin. 2005–2012
- Research Associate, The Gurdon Institute, Cambridge, UK. Advisor: Enrique Amaya. 2003–2005
HONORS AND AWARDS
- Provost’s Distinguished Associate Professor 2021. Georgetown University
- Biology Graduate Student Outstanding Mentor Award 2021. Biology Dept., Georgetown University
- Harry Weaver Neuroscience Scholar Award 2019. National Multiple Sclerosis Society
- Georgetown Distinguished Investigator 2017. Georgetown University
- Roger D. Semerad Award for Research in the Neurosciences 2016. TurnFirst Foundation
- Partners in Research Award 2015. Georgetown University Medical Center
- Music For the Mind Award 2014. Georgetown University Medical Center
PROFESSIONAL SERVICE
Peer Reviewer
- Member, Cellular and Molecular Biology of Glia Study Section (CMBG), NIH. 2022–2026
- Programmatic Panel, Multiple Sclerosis Research Program (MSRP), DoD/CDMRP. 2021–2024
- Biomedical Review Committee (A), National Multiple Sclerosis Society. 05/2018–Present
- Glial Pilot Review Committee, National Multiple Sclerosis Society. 05/2015–02/2018
Ad hoc grant reviewer: Regenerative Rehabilitation (RRD0), Dept. of Veterans Affairs.
ZRG1 MDCN-G (03), NIH, NJ Brain Commission on Brain Injury Research, Spinal Cord Injury Research Program (SCIRP), CDMRP, UK Multiple Sclerosis Society, MRC UK, BBSRC UK, International Progressive MS Alliance, ARSEP French MS Society, Telethon Italy
Ad hoc journal reviewer: Nature Chemical Biology; Journal of Neuroscience; Journal of Neurochemistry; Experimental Neurology; Neuropharmacology; Frontiers in Neuroscience; Acta Neuropathologica; Cell and Molecular Neurobiology; Alcoholism: Clinical and Experimental Research; NeuroReport; Annals of Neurology; Neuroscience; Rejuvenation Research; Journal of Neuroscience Research; Journal of Biomedical Sciences; Acta Neuropathologica Communications; Brain Communications; Nature Communications; Neurochemical Research; Journal of Neuroimmunology; Frontiers in Cell and Developmental Biology
Editorial
- Associate Editor, Frontiers in Immunology, Multiple Sclerosis and Neuroimmunology. 2022
- Section Editor, Current Opinions in Pharmacology, 2022 Special Issue: Remyelination. 2021
- Guest Editor, Neuropharmacology, Special Issue: Oligodendrocytes in Health and Disease. 2016
- Guest Editor, Stem Cells International, Special Issue: Neural Stem and Progenitor Cells in Nervous System Function and Therapy 2016
- Associate Editor, Frontiers in Neuroscience, Neurodegeneration. 2015–Present
Symposium Organizer
- “Regulation of neuroinflammation in CNS remyelination.”, Symposium, XVI European Meeting on Glial Cells in Health and Disease 2023. Berlin, Germany. 07/2023
- “Strategies for promoting CNS remyelination”, Plenary Lecture, Presidential Symposium, American Society of Neurochemistry 2017, Little Rock, AK. 03/2017
RESEARCH SUPPORT
Active
- R21, National Institutes of Aging (NIA), NIH. PI: HUANG. 02/01/22-06/30/24
- MSRP Investigator-Initiated Research Award, DoD/CDMRP. PI: HUANG. 08/01/21-06/30/24
- Harry Weaver Neuroscience Scholar Award, NMSS. PI: HUANG. 07/01/19-06/30/24
- R01, NINDS, NIH. PI: HUANG. 07/01/18-06/30/24 (NCE)
Completed
- J Pharma (Sponsored Research). 10/01/20-9/30/21
- JW Holdings Pharmaceutical (Service Contract). 11/01/20-05/31/21
- MSRP Investigator-Initiated Research Award, CDMRP . 10/01/17-09/31/20
- Frequency Therapeutics (Service Contract). 06/01/18-4/30/20
- R21, NINDS, NIH. 07/15/15-06/30/18
- Roger D. Semerad Award. 01/01/17-12/31/18
- Pilot Project Grant (PP-1606-24509), NMSS. 11/01/16-10/31/17
- Research Grant (RG5022A1/1), NMSS. 10/01/14-09/31/1
- Pilot Project Grant (PP2159), NMSS. 04/01/14-03/31/15
PUBLICATIONS
- Donovan APA, Rosko L, Ellegood J, Redhead Y, Green JBA, Lerch JP, Huang JK, Basson MA. Pervasive cortical and white matter anomalies in a mouse model for CHARGE syndrome. J Anat. 2023 Mar 13;. doi: 10.1111/joa.13856. [Epub ahead of print] PubMed PMID: 36914558.
- Yamazaki R, Osanai Y, Kouki T, Huang JK, Ohno N. Pharmacological treatment promoting remyelination enhances motor function after internal capsule demyelination in mice. Neurochem Int. 2023 Mar;164:105505. doi: 10.1016/j.neuint.2023.105505. Epub 2023 Feb 6. PubMed PMID: 36754122.
- Rosko LM, Gentile T, Smith VN, Manavi Z, Melchor GS, Hu J, Shults NV, Albanese C, Lee Y, Rodriguez O, Huang JK. Cerebral Creatine Deficiency Affects the Timing of Oligodendrocyte Myelination. J Neurosci. 2023 Feb 15;43(7):1143-1153. doi: 10.1523/JNEUROSCI.2120-21.2022. Epub 2023 Feb 2. PubMed PMID: 36732069; PubMed Central PMCID: PMC9962777.
- Huang JK, DeSilva TM. Making myelin regenerate: Factors to consider. Curr Opin Pharmacol. 2023 Feb;68:102326. doi: 10.1016/j.coph.2022.102326. Epub 2022 Dec 10. PubMed PMID: 36512980.
- Hu J, Baydyuk M, Huang JK. Impact of amino acids on microglial activation and CNS remyelination. Curr Opin Pharmacol. 2022 Oct;66:102287. doi: 10.1016/j.coph.2022.102287. Epub 2022 Sep 5. Review. PubMed PMID: 36067684.
- Rouillard ME, Hu J, Sutter PA, Kim HW, Huang JK, Crocker SJ. The Cellular Senescence Factor Extracellular HMGB1 Directly Inhibits Oligodendrocyte Progenitor Cell Differentiation and Impairs CNS Remyelination. Front Cell Neurosci. 2022;16:833186. doi: 10.3389/fncel.2022.833186. eCollection 2022. PubMed PMID: 35573828; PubMed Central PMCID: PMC9095917.
- Creighton BA, Afriyie S, Ajit D, Casingal CR, Voos KM, Reger J, Burch AM, Dyne E, Bay J, Huang JK, Anton ES, Fu MM, Lorenzo DN. Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A. Elife. 2021 Nov 23;10. doi: 10.7554/eLife.69815. PubMed PMID: 34812142; PubMed Central PMCID: PMC8610419.
- Yamazaki R, Osanai Y, Kouki T, Shinohara Y, Huang JK, Ohno N. Macroscopic detection of demyelinated lesions in mouse PNS with neutral red dye. Sci Rep. 2021 Aug 19;11(1):16906. doi: 10.1038/s41598-021-96395-4. PubMed PMID: 34413421; PubMed Central PMCID: PMC8377033.
- Yamazaki R, Ohno N, Huang JK. Acute motor deficit and subsequent remyelination-associated recovery following internal capsule demyelination in mice. J Neurochem. 2021 Mar;156(6):917-928. doi: 10.1111/jnc.15142. Epub 2020 Aug 14. PubMed PMID: 32750162; PubMed Central PMCID: PMC8048697.
- Baydyuk M, Morrison VE, Gross PS, Huang JK. Extrinsic Factors Driving Oligodendrocyte Lineage Cell Progression in CNS Development and Injury. Neurochem Res. 2020 Mar;45(3):630-642. doi: 10.1007/s11064-020-02967-7. Epub 2020 Jan 29. Review. PubMed PMID: 31997102; PubMed Central PMCID: PMC7058689.
- Morrison VE, Smith VN, Huang JK. Retinoic Acid Is Required for Oligodendrocyte Precursor Cell Production and Differentiation in the Postnatal Mouse Corpus Callosum. eNeuro. 2020 Jan/Feb;7(1). doi: 10.1523/ENEURO.0270-19.2019. Print 2020 Jan/Feb. PubMed PMID: 31879367; PubMed Central PMCID: PMC6977210.
- Melchor GS, Khan T, Reger JF, Huang JK. Remyelination Pharmacotherapy Investigations Highlight Diverse Mechanisms Underlying Multiple Sclerosis Progression. ACS Pharmacol Transl Sci. 2019 Dec 13;2(6):372-386. doi: 10.1021/acsptsci.9b00068. eCollection 2019 Dec 13. Review. PubMed PMID: 32259071; PubMed Central PMCID: PMC7088971.
- Rosko L, Smith VN, Yamazaki R, Huang JK. Oligodendrocyte Bioenergetics in Health and Disease. Neuroscientist. 2019 Aug;25(4):334-343. doi: 10.1177/1073858418793077. Epub 2018 Aug 20. Review. PubMed PMID: 30122106; PubMed Central PMCID: PMC6745601.
- Baydyuk M, Cha DS, Hu J, Yamazaki R, Miller EM, Smith VN, Kelly KA, Huang JK. Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14290-14299. doi: 10.1073/pnas.1819343116. Epub 2019 Jun 24. PubMed PMID: 31235582; PubMed Central PMCID: PMC6628798.
- Chamberlain KA, Chapey KS, Nanescu SE, Huang JK. Creatine Enhances Mitochondrial-Mediated Oligodendrocyte Survival After Demyelinating Injury. J Neurosci. 2017 Feb 8;37(6):1479-1492. doi: 10.1523/JNEUROSCI.1941-16.2016. Epub 2017 Jan 9. PubMed PMID: 28069926; PubMed Central PMCID: PMC5299567.
- Psachoulia K, Chamberlain KA, Heo D, Davis SE, Paskus JD, Nanescu SE, Dupree JL, Wynn TA, Huang JK. IL4I1 augments CNS remyelination and axonal protection by modulating T cell driven inflammation. Brain. 2016 Dec;139(Pt 12):3121-3136. doi: 10.1093/brain/aww254. Epub 2016 Oct 25. PubMed PMID: 27797811; PubMed Central PMCID: PMC5382940.
- Chamberlain KA, Nanescu SE, Psachoulia K, Huang JK. Oligodendrocyte regeneration: Its significance in myelin replacement and neuroprotection in multiple sclerosis. Neuropharmacology. 2016 Nov;110(Pt B):633-643. doi: 10.1016/j.neuropharm.2015.10.010. Epub 2015 Oct 22. Review. PubMed PMID: 26474658; PubMed Central PMCID: PMC4841742.
- Huang JK, Káradóttir RT. Oligodendrocytes in health and disease. Neuropharmacology. 2016 Nov;110(Pt B):537-538. doi: 10.1016/j.neuropharm.2016.06.034. Epub 2016 Aug 20. PubMed PMID: 27553122.
- Xie T, Vora A, Mulcahey PJ, Nanescu SE, Singh M, Choi DS, Huang JK, Liu CC, Sanders DP, Hahm JI. Surface Assembly Configurations and Packing Preferences of Fibrinogen Mediated by the Periodicity and Alignment Control of Block Copolymer Nanodomains. ACS Nano. 2016 Aug 23;10(8):7705-20. doi: 10.1021/acsnano.6b03071. Epub 2016 Jul 29. PubMed PMID: 27462904.
- Walker T, Huang J, Young K. Neural Stem and Progenitor Cells in Nervous System Function and Therapy. Stem Cells Int. 2016;2016:1890568. doi: 10.1155/2016/1890568. Epub 2016 Aug 14. PubMed PMID: 27579042; PubMed Central PMCID: PMC4989086.
- de la Fuente AG, Errea O, van Wijngaarden P, Gonzalez GA, Kerninon C, Jarjour AA, Lewis HJ, Jones CA, Nait-Oumesmar B, Zhao C, Huang JK, ffrench-Constant C, Franklin RJ. Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation. J Cell Biol. 2015 Dec 7;211(5):975-85. doi: 10.1083/jcb.201505119. PubMed PMID: 26644513; PubMed Central PMCID: PMC4674280.
- Moyon S, Dubessy AL, Aigrot MS, Trotter M, Huang JK, Dauphinot L, Potier MC, Kerninon C, Melik Parsadaniantz S, Franklin RJ, Lubetzki C. Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. J Neurosci. 2015 Jan 7;35(1):4-20. doi: 10.1523/JNEUROSCI.0849-14.2015. PubMed PMID: 25568099; PubMed Central PMCID: PMC6605244.
- Huang CC, Bose JK, Majumder P, Lee KH, Huang JT, Huang JK, Shen CK. Metabolism and mis-metabolism of the neuropathological signature protein TDP-43. J Cell Sci. 2014 Jul 15;127(Pt 14):3024-38. doi: 10.1242/jcs.136150. Epub 2014 May 23. PubMed PMID: 24860144.
- Syed YA, Baer A, Hofer MP, González GA, Rundle J, Myrta S, Huang JK, Zhao C, Rossner MJ, Trotter MW, Lubec G, Franklin RJ, Kotter MR. Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination. EMBO Mol Med. 2013 Dec;5(12):1918-34. doi: 10.1002/emmm.201303123. Epub 2013 Oct 21. PubMed PMID: 24293318; PubMed Central PMCID: PMC3914530.
- Camacho A, Huang JK, Delint-Ramirez I, Yew Tan C, Fuller M, Lelliott CJ, Vidal-Puig A, Franklin RJ. Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. Eur J Neurosci. 2013 Sep;38(5):2672-83. doi: 10.1111/ejn.12281. Epub 2013 Jun 14. PubMed PMID: 23763823.
- Huang JK, Ferrari CC, Monteiro de Castro G, Lafont D, Zhao C, Zaratin P, Pouly S, Greco B, Franklin RJ. Accelerated axonal loss following acute CNS demyelination in mice lacking protein tyrosine phosphatase receptor type Z. Am J Pathol. 2012 Nov;181(5):1518-23. doi: 10.1016/j.ajpath.2012.07.011. Epub 2012 Aug 31. PubMed PMID: 22940073; PubMed Central PMCID: PMC3483537.
- Huang JK, Franklin RJ. Current status of myelin replacement therapies in multiple sclerosis. Prog Brain Res. 2012;201:219-31. doi: 10.1016/B978-0-444-59544-7.00011-1. Review. PubMed PMID: 23186717.
- Huang JK, Fancy SP, Zhao C, Rowitch DH, Ffrench-Constant C, Franklin RJ. Myelin regeneration in multiple sclerosis: targeting endogenous stem cells. Neurotherapeutics. 2011 Oct;8(4):650-8. doi: 10.1007/s13311-011-0065-x. Review. PubMed PMID: 21904791; PubMed Central PMCID: PMC3250284.
- Huang JK, Franklin RJ. Regenerative medicine in multiple sclerosis: identifying pharmacological targets of adult neural stem cell differentiation. Neurochem Int. 2011 Sep;59(3):329-32. doi: 10.1016/j.neuint.2011.01.017. Epub 2011 Feb 12. Review. PubMed PMID: 21300122.
- Huang JK, Jarjour AA, Ffrench-Constant C, Franklin RJ. Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis. Expert Rev Neurother. 2011 Apr;11(4):467-8. doi: 10.1586/ern.11.34. PubMed PMID: 21469916.
- Huang JK, Jarjour AA, Nait Oumesmar B, Kerninon C, Williams A, Krezel W, Kagechika H, Bauer J, Zhao C, Baron-Van Evercooren A, Chambon P, Ffrench-Constant C, Franklin RJM. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat Neurosci. 2011 Jan;14(1):45-53. doi: 10.1038/nn.2702. Epub 2010 Dec 5. PubMed PMID: 21131950; PubMed Central PMCID: PMC4013508.
- Dhaunchak AS, Huang JK, De Faria Junior O, Roth AD, Pedraza L, Antel JP, Bar-Or A, Colman DR. A proteome map of axoglial specializations isolated and purified from human central nervous system. Glia. 2010 Dec;58(16):1949-60. doi: 10.1002/glia.21064. PubMed PMID: 20830807.
- Fancy SP, Kotter MR, Harrington EP, Huang JK, Zhao C, Rowitch DH, Franklin RJ. Overcoming remyelination failure in multiple sclerosis and other myelin disorders. Exp Neurol. 2010 Sep;225(1):18-23. doi: 10.1016/j.expneurol.2009.12.020. Epub 2010 Jan 4. Review. PubMed PMID: 20044992; NIHMSID:NIHMS232929.
- Pedraza L, Huang JK, Colman D. Disposition of axonal caspr with respect to glial cell membranes: Implications for the process of myelination. J Neurosci Res. 2009 Nov 15;87(15):3480-91. doi: 10.1002/jnr.22004. PubMed PMID: 19170162.
- Huang JK, Dorey K, Ishibashi S, Amaya E. BDNF promotes target innervation of Xenopus mandibular trigeminal axons in vivo. BMC Dev Biol. 2007 May 31;7:59. doi: 10.1186/1471-213X-7-59. PubMed PMID: 17540021; PubMed Central PMCID: PMC1899173.
- Huang JK, Phillips GR, Roth AD, Pedraza L, Shan W, Belkaid W, Mi S, Fex-Svenningsen A, Florens L, Yates JR 3rd, Colman DR. Glial membranes at the node of Ranvier prevent neurite outgrowth. Science. 2005 Dec 16;310(5755):1813-7. doi: 10.1126/science.1118313. Epub 2005 Nov 17. PubMed PMID: 16293723.
- Phillips GR, Huang JK, Wang Y, Tanaka H, Shapiro L, Zhang W, Shan WS, Arndt K, Frank M, Gordon RE, Gawinowicz MA, Zhao Y, Colman DR. The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron. 2001 Oct 11;32(1):63-77. doi: 10.1016/s0896-6273(01)00450-0. PubMed PMID: 11604139.
- Pedraza L, Huang JK, Colman DR. Organizing principles of the axoglial apparatus. Neuron. 2001 May;30(2):335-44. doi: 10.1016/s0896-6273(01)00306-3. Review. PubMed PMID: 11394997.
- Tait S, Gunn-Moore F, Collinson JM, Huang J, Lubetzki C, Pedraza L, Sherman DL, Colman DR, Brophy PJ. An oligodendrocyte cell adhesion molecule at the site of assembly of the paranodal axo-glial junction. J Cell Biol. 2000 Aug 7;150(3):657-66. doi: 10.1083/jcb.150.3.657. PubMed PMID: 10931875; PubMed Central PMCID: PMC2175192.
- Gould R, Freund C, Palmer F, Knapp PE, Huang J, Morrison H, Feinstein DL. Messenger RNAs for kinesins and dynein are located in neural processes. Biol Bull. 1999 Oct;197(2):259-60. doi: 10.2307/1542638. PubMed PMID: 10573845.
- Wang ZY, Qiu QQ, Gurrieri M, Huang J, Deuel TF. WT1, the Wilms' tumor suppressor gene product, represses transcription through an interactive nuclear protein. Oncogene. 1995 Mar 16;10(6):1243-7. PubMed PMID: 7700651.
- Wang ZY, Qiu QQ, Huang J, Gurrieri M, Deuel TF. Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways. Oncogene. 1995 Feb 2;10(3):415-22. PubMed PMID: 7845666.
PATENTS FILED
- Huang JK and Baydyuk M. Composition and methods for treating inflammatory neurological disorders. Provisional Application 62/740,175. Filed: 10/02/2018
- Huang JK. Composition and methods of using interleukin-4 induced gene 1 (IL4I1). PCT/US2015/04919. Filed: 09/10/2014
INVITED TALKS/SEMINARS
- Symposium: Regulation of neuroinflammation in CNS remyelination. XVI European Meeting on Glial Cells in Health and Disease 2023. Berlin, Germany. 07/08/23
- Symposium: Neuroinflammation: Translation at the Brain-Immune Interface. Spring Brain Conference 2023. Sedona, AZ. 04/26/23
- Symposium: Astrocytes and microglia in neural repair: new insights across model organisms and injury types. American Society for Neurochemistry 2023. Lexington, KY. 03/21/23
- Workshop Panel: Remyelination Therapies: What Is Holding Us Back and Can We Fix It? American Society for Neurochemistry 2023. Lexington, KY. 03/20/23
- Symposium: Cellular and Molecular Mechanisms of Myelin Maintenance and Remyelination. American Society for Neurochemistry 2022. Roanoke, VA. 04/11/22
- MSVirtual2020, 8th Joint ACTRIMS-ECTRIMS meeting (Virtual). 09/12/20
- Neuroscience Trainee-Sponsored Seminar Series, Center for Neuroscience Research at Children's National Medical Center, Washington, DC (Virtual). 06/15/20
- Neural Restoration Effort Symposium, Georgetown University, Washington, DC. 12/10/19
- NMSS Tykeson Fellows Conference on Multiple Sclerosis, Atlanta, GA. 11/14/19
- Department of Physiology, Howard University, Washington, DC. 09/16/19
- Department of Neuroscience, Washington University in St. Louis, St. Louis, MO. 02/18/19
- Neuroimmunology Seminar, Dept Neurology, Johns Hopkins University School of Medicine, Baltimore, MD. 12/04/18
- Neuroscience Seminar Series, University of Connecticut Health Center, CT. 10/16/18
- Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH. 10/08/18
- NIH Neuron-Glia Interactions Special Interest Group, National Institutes of Health, Bethesda, MD. 06/07/18
- Neuroscience Seminar Series, Sanofi, Neuroscience Research and Therapeutic Area, Framingham, MA. 10/02/17
- Center for Cell Reprogramming, Georgetown University Medical Center, Washington, DC. 09/14/17
- Immune Cells and the CNS, Satellite Meeting - International Society for Neurochemistry, Château de Cély, France. 08/18/17
- NGP Summer 2017 Seminar Series, Neuroscience Graduate Program, University of Virginia, Charlottesville, VA. 06/06/17
- Presidential Symposium, American Society for Neurochemistry 2017, Little Rock, AK. 03/22/17
- Neurobreakfast Seminar, Department of Neuroscience, Georgetown University Medical Center, Washington, DC. 01/25/17
- Tulane Brain Institute Seminar, The Tulane Brain Institute, Tulane University, New Orleans, LA. 01/18/17
- Windows in Translation Seminar, Dept of Medicine, Georgetown University Medical Center, Washington, DC. 12/01/16
- GW Institute for Neuroscience Seminar, George Washington School of Medicine, Washington, DC. 11/10/16
- NIH-IRA-MedImmune Mini-Symposia on “Tissue homeostasis, repair, regeneration, and fibrosis”, National Institutes of Health, Bethesda, MD. 05/02/16
- Pharmacology Seminar, Department of Pharmacology, Georgetown University Medical Center, Washington, DC. 02/25/16
- Center for Plasticity and Recovery Seminar, National Rehabilitation Hospital, Washington, DC. 01/20/16
- Neurology Grand Rounds, Department of Neurology, Georgetown University Medical Center, Washington, DC. 10/29/15
- Neuroimmunology Seminar, Division of Neuroimmunology & Neurovirology, NINDS, National Institutes of Health, Bethesda, MD. 06/01/15
- Neuroimmunology Seminar, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD. 05/26/15
- Brown Bag Talk, Soft Matter Institute, Georgetown University. 02/17/15
- Nanosymposium: Demyelinating Disorders, Society for Neuroscience 2014, Washington, DC. 11/15/14
- GWU Biology Spring Seminar, Department of Biology, George Washington University, Washington, DC. 02/07/14
- Neurobreakfast Seminar, Department of Neuroscience, Georgetown University Medical Center, Washington, DC. 04/24/13
UNIVERSITY SERVICE
University
- Georgetown University Research Integrity Committee. 2022-
- Georgetown University IACUC Committee. 2021-
- Georgetown University Shared Resources Oversight Committee (SROC). 2019-
- Georgetown University Faculty Senate Steering Committee. 2018-2019
- Georgetown University Faculty Senate. 2017-2020
- Admissions Committee, Interdisciplinary Program in Neuroscience (IPN). 2016
- Executive Committee, Interdisciplinary Program in Neuroscience (IPN). 2014-2022
- Student Advisory Council (SAC), Interdisciplinary Program in Neuroscience (IPN). 2014-2017
- Georgetown University IACUC Committee. 2014-2016
Departmental
- Merit Review Committee. 2021-
- Neurobiology Faculty Search Committee. 2018-2019
- Committee of Graduate Students and Studies (CGSS). 2018-2021
- Biology/Center for Cell Reprogramming Joint Faculty Search Committee. 2016-2019
- Organizer, Biology Faculty Chalk Talk. 2015-2017
- Co-advisor, HHMI Undergraduate Summer Research Program. 2014
- Neurobiology Faculty Search Committee. 2013-2014
- Undergraduate Academic Advisor Neurobiology Major, 12–15 students at one time. 2013-
GRADUATE COURSES
BIOL-516 – Neuro Journal Club (1 credit), Fall/Spring 2020–Present
BIOL-516 – MCB Journal Club (1 credit), Fall/Spring 2016, 2017, 2018, 2019.
GUEST LECTURES (graduate and undergraduate)
NSCI-558 - Molecular Mechanisms of Neurodegeneration, Spring 2020, 2021, 2022, 2023. Senescence
NSCI-558 - Molecular Mechanisms of Neurodegeneration, Spring 2019. Multiple Sclerosis
NSCI-503 – Systems & Cognitive Neuroscience (3 credits), Spring 2018, 2019. Glia and multiple sclerosis
BIOL-508 – Integrated Biology Core Course (3 credits), Spring 2017, 2018. Neuron-glia interactions
IPN Summer Course, Summer 2015. Glia Biology and Glia-Neuronal Interactions
BIOL-370 – Neurodisorders, Spring 2014. Multiple Sclerosis
IPN NeuroFest, Summer 2013-2016. Oligodendrocyte-neuron interactions
Fundamentals of Neuroscience, GU High School Program, Summer 2013. Glial cells of the nervous system
PHIL-020 – Intro to Philosophy, Spring 2013. Philosophy of science
PH.D. THESIS STUDENTS
Mia Cozart, Biology Graduate Training Program (2020–Present)
Zeeba Manavi, Biology Graduate Training Program (2020–Present)
Phillip Gross, IPN Graduate Training Program (2019–Present)
Joan Reger, Biology Graduate Training Program (2018–Present); Co-advisor: Meng Meng Fu, NIH
George Melchor, IPN Graduate Training Program (2018–Present)
Lauren Rosko, IPN Graduate Training Program (2017–2021).
Jingwen Hu, Biology Graduate Training Program (2016–Present).
Stephanie Davis, IPN Graduate Training Program (2015–2018)
Vivianne Morrison, IPN Graduate Training Program (2014–2019).
Kelly Chamberlain, IPN Graduate Training Program (2013–2016).
CO-ADVISEES
Danna Cunningham, IPN Graduate Training Program (2022–Present). Co-supervisor Dr. Bill Rebeck, Neuroscience, GUMC
Nathanael Lee, IPN/NIH Graduate and MD/PhD Program (2015–2019). Co-supervisor with Dr. Daniel Reich, NINDS/NIH
Jeremiah Paskus, IPN/NIH Graduate Training Program (2015–2019). Co-supervisor Dr. Katherine Roche, NINDS/NIH
POSTDOCTORAL FELLOWS/RESEARCH STAFF
Nataliia Shults, M.D./Ph.D. (2020–Present)
Mi-Hye Lee, Ph.D. (2019–2023)
Erqiu Li, Ph.D. (2019–2021)
Maryna Baydyuk, Ph.D. (2017–Present)
Reiji Yamazaki, Ph.D. (2017–2020)
Rafal Olszewski, Ph.D. (2013–2014)
Konstantina Psachoulia, Ph.D. (2013–2016)
Sonia Nanescu, Ph.D. (2013–2018)
UNDERGRADUATE COURSES
BIOL-414 – Neurodisorders (3 credits), Fall 2016–Present
BIOL-363 – Cell Biology (3 credits), Spring 2015, 2017, 2018, Fall 2022
BIOL-170 – Cell and Developmental Biology (4 credits), Spring 2013, 2014
BIOL-424 – Regenerative Biology and Medicine (3 credits), Fall 2013, 2014, 2015
BIOL-401 – Senior Seminar in Biology (1 credit), Fall, 2013, 2014, 2015
BIOL-341 – RISE-I:Rsrch Intsv Sr Exprnce (3 credits), 2013–Present
BIOL-300 – Research Tutorial (3 credits), 2013–Present
COMMUNITY OUTREACH
- Speaker and Donor Engagement, National MS Society, Capital Chapter. 05/2023
- Speaker, Virtual Donor Event, National MS Society, Maryland. 02/2021
- Podcast, Neurology Learning Network, “Jeffrey Huang, PhD, Talks Remyelination Strategies in Multiple Sclerosis”. 10/2020
- Podcast, Real Talk MS, “Episode 92: MS Research with Dr. Jeffrey Huang”. 06/2019
- Speaker, National Multiple Sclerosis Society’s 15th Annual On the Move Luncheon, Washington DC. 04/2019
- Donor Engagement Speaker, Partners in Research, GUMC. 05/2016
- Panelist, Medical School Grand Rounds, Subject “Multiple Sclerosis”, Georgetown University School of Medicine. 03/2016
- Speaker, Educational seminar on animal models of multiple sclerosis, Division of Comparative Medicine (DCM), Georgetown University. 08/2015
- Judge, Undergraduate Research Conference, Georgetown University. 2051-
- Speaker, “Regenerative medicine in multiple sclerosis”, 1st Annual Georgetown University Neuroscience Public Lecture, Brain Awareness Week, Washington DC. 03/2015
- Panelist, “How to get a postdoc” Workshop, Georgetown University BGE and MCGSO. 03/2015
- Speaker, “MS: Regenerative Medicine and Immunomodulation”, Symposium on Neuromuscular Disease: Diagnosis, Treatment, Research and Ethical Issues, International Visitor Leadership Program, Georgetown University. 02/2015
- Faculty Reviewer, Junior Science and Humanities Symposium. 11/2014
- Speaker, “Making it in Academia”, Cambridge University Careers Service, University of Cambridge. 12/2013
- Speaker, “Therapeutic strategies for multiple sclerosis”, National Multiple Sclerosis Society, Capital Chapter. 10/2013
PRESS
- “Huang Receives Award to Research MS Treatment”, Georgetown University. 04/2019
- “A Piece of the MS Puzzle”, Georgetown University. 03/2015